Renowned biologist David Botstein led the effort to sequence the yeast genome. Botstein was among the first to see the potential for genomics to create new disease therapies that are individually tailored.
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- ID: 15710
- Source: DNALC.DNAi
David Botstein (sitting with Pat Brown) talks about how innovations in genomics might lead to personalized medicine.
David Botstein talks about how tumor typing using genome-wide analysis will help doctors determine the most appropriate treatments for their patients.
David Botstein discusses how identifying the molecular mechanisms of cancer will lead to the development of improved therapies.
Yeast was the first eukaryote organism to have its entire genome sequenced. It has remained at the forefront of genetics research because it is quick and easy to grow.
David Botstein talks about the goal of using microarray analysis to improve cancer diagnosis.
Model organisms such as yeast, bacteria, the mouse and the fruit fly are used by researchers to study biological systems. The genomes of these organisms have been mapped and sequenced.
Comparing the early days of molecular biology research to today's informatics - heavy genome era.
Model organisms researchers: (clockwise from top left) David Botstein, Mario Capecchi, John Sulston, Ewan Birney, and Sydney Brenner.
A human is a complicated organism, and it is considered unethical to do many kinds of experiments on human subjects. For these reasons, biologists often use simpler “model” organisms that are easy to keep and manipulate in the laboratory.