A unique cluster of genes, Jim Kent
Interviewee: Jim Kent. Some 220 different genes comprise what is known as the human leukocyte antigen (HLA) gene complex. These genes are responsible for making proteins that reside on our cell's surfaces and guard against invasion by foreign matter such as bacteria or viruses. These same genes are suspected of playing a role in certain autoimmune diseases. (DNAi Location: Genome > Tour > Genome spots > Chromosome 6: Immunity genes > A unique cluster of genes)
You'll often see clusters of genes. A very important one is, for instance, on chromosome 6. There's a section, the major histo-compatibility locus we call it. And this is an area that is, actually, it's kind of the heart of your immune system all clustered together in this, this relatively dense area on chromosome 6. And it's what leads to rejection when you, you transplant one, one human organ into another, you know, unless they're, unless you have compatible genes at this locus it just won't go, it will be recognized as foreign and attacked. And yet this is sort of, this is the same area where the AIDS virus is doing its work and exploiting things and inside this major histo-compatibility locus.
gene clusters,chromosome 6,human leukocyte antigen,jim kent,aids virus,dense area,autoimmune diseases,human organ,dnai,gene name,interviewee,histo,locus,chromosomes,genes,immunity,immune system,rejection,bacteria,proteins
- ID: 15313
- Source: DNALC.DNAi
- Download: Theora Video MPEG 4 Video
Related Content
15401. Chromosome 6: HLA genes and the human immune system, Matt Ridley
Matt Ridley talks about chromosome 6, HLA genes and the human immune system.
15415. Chromosome 20: gene for adenosine deaminase, Matt Ridley
Matt Ridley talks about chromosome 20, gene for adenosine deaminase.
548. Model Center
Model organisms share with humans many key biochemical and physiological functions that have been conserved (maintained) by evolution.
15312. Banding appears in dyed chromosomes, Jim Kent
Jim Kent talks about banding appears in dyed chromosomes.
15407. Chromosome 12: HOX genes of development, Matt Ridley
Matt Ridley talks about chromosome 12, HOX genes of development.
15309. Junk DNA in the human genome, Jim Kent.
Jim Kent talks about junk DNA in the human genome.
15410. Chromosome 15: Prader-Willi's disease, or Angelman's syndrome, Matt Ridley
Matt Ridley talks about chromosome 15, Prader-Willi's disease, or Angelman's syndrome
15404. Chromosome 9: gene for blood group, Matt Ridley
Matt Ridley talks about chromosome 9, gene for blood group.
15399. Chromosome 4: Huntington's Disease, Matt Ridley
Matt Ridley talks about chromosome 4, Huntington's Disease.
15400. Chromosome 5: genes involved in asthma and other allergies, Matt Ridley
Matt Ridley talks about chromosome 5, genes involved in asthma and other allergies