Junk DNA in the human genome, Jim Kent.
Interviewee: Jim Kent. Junk DNA in the human genome.
It's not clear how much of the genome is doing anything. We know that about one percent of it seems to be involved with actively producing proteins, sort of the moving parts of the cell. But then what the rest does is fairly mysterious. We get a little bit of a handle on this by comparing it with the mouse and from mouse comparisons and seeing what's conserved between mouse and human. It looks like, you know, perhaps five percent is serving some function. And some of that is things that we know about. Some of it is involved with turning genes on and off, rather than the actual genes themselves.
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Jim Kent talks about a farm of computers.
Jim Kent, the author of the assembly program for the public sequence, talks about the challenge of reassembling the genome.
Jim Kent talks about dealing with sequencing data.
Jim Kent talks about cell division and DNA.
Jim Kent talks about the data structure of the human genome: poetry or prose?
Jim Kent talks about transposons and repetitive elements in the human genome.
James Watson talks abput repetitve elements, junk DNA, transposons, and compartative genomics.
Leroy Hood talks about audacious idea of sequencing the human genome.
Jim Kent talks about telomeres and cell death.
Ewan Birney, one of the leading analysts of the Human Genome Project, takes you on a chromosome tour.