Mitochondria from the beginning, Douglas Wallace
Interviewee: Douglas Wallace. Molecular geneticist Douglas Wallace talks about the origin of our mitochondria and the DNA within. (DNAi Location: Applications > Human origins > Gene genealogy > Mitochondrial DNA (mtDNA) > Mitochondrial and mtDNA)
Mitochondrial DNA is a small piece of DNA that's located in structures outside the nucleus, these structures called the mitochondria. The mitochondria are actually ancient bacteria that entered the early cells when they were still just single living cells about three billion years ago and have formed a symbiotic relationship in which the mitochondria live as a conolinear bacteria inside our cells. Now because they are bacteria they have their own information system, which is DNA and they convert that information into structures in the form of RNA and then proteins.
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Molecular geneticist Douglas Wallace talks about the way mitochondrial DNA is inherited.
Geneticist Douglas Wallace explains a method of mapping a population's history using the mutations accumulated by its members.
DNAFTB Animation 30: Ivan Wallin presents his idea that mitochondria and chloroplasts were once free-living organisms.
Mitochondrial DNA pioneer Douglas Wallace speaks about a possible migration of people from Europe to the Americas, 15,000 years ago.
Evolutionary geneticist Svante Paabo talks about the environments that will best preserve ancient DNA.
Mitochondrial DNA research pioneer Douglas Wallace speaks about mitochondrial DNA and theories of human evolution.
Mitochondrial DNA research pioneer Douglas Wallace speaks about the populations he samples and the direct application of the research.
This illustration shows the two major mitochondrial DNA lineages. The lower branch includes only African populations. The upper branch has both African and non-African members.
Mitochondria contain a circular genome molecule, tightly packed with genes.
Mitochondrial DNA pioneer Douglas Wallace explains the movement of different lineages of humans from Africa into Europe and Asia.