Isolating ancient DNA, Svante Paabo
Interviewee: Svante Paabo. Evolutionary geneticist Svante Paabo speaks about the limitations of working with DNA from fossils. (DNAi Location: Applications > Human origins > Comparisons > DNA > Isolating ancient DNA)
So what we are actually, now, wondering would of course be to go back really far in time and isolate DNA from dinosaurs that are millions of years old and so on. Unfortunately from what we know about the chemical stability of DNA, how the agents such as water or background radiation affect DNA, that will as far as we can tell, be impossible, since probably within 100,000 to 500,000 years, we can actually calculate that there is no reason to expect that DNA will survive in fossils.
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Geneticist Mark Stoneking, co-author of an early mitochondrial DNA paper, talks about the competing theories of human origins.
Evolutionary geneticist Svante Paabo talks about the environments that will best preserve ancient DNA.
Mutations and the molecular clock.
Molecular geneticist Douglas Wallace talks about the origin of our mitochondria and the DNA within.
Evolutionary geneticist Svante Paabo talks about his team's pioneering work with ancient Neandertal mtDNA.
Author Steve Olson talks about the stable and isolated history of the San people of Southern Africa, who are sometimes known as "Bushmen."
Evolutionary geneticist Svante Paabo talks about the consequences of losing our sense of smell.
Human origins expert Chris Stringer talks about the relationship between Neandertals and humans.
Evolutionary geneticist Svante Paabo talks about the possible outcomes of human and chimp gene comparisons.
Evolutionary geneticist Svante Paabo speaks about differences between active human and chimp genes in different organs