Comparing chimp and human genes, Svante Paabo
Interviewee: Svante Paabo. Evolutionary geneticist Svante Paabo speaks about differences between active human and chimp genes in different organs. (DNAi Location: Applications > Human origins > Comparisons > DNA > Comparing chimp and human genes)
So what we looked at were three different tissues. We looked at blood, we looked at liver and we looked at brain. And what we find is that about as many genes differ in each of these tissues, about 15/18% of the genes differ. But in the brain what's special is that when we compare humans to chimp, and compare also to an orangutan, what we find is that most of these differences that happened on the evolutionary line to humans actually happened in the ancestor to humans, and not in the ancestor to the chimpanzee. So it seems that our brain has changed particularly much on the line to human.
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Evolutionary geneticist Svante Paabo talks about the possible outcomes of human and chimp gene comparisons.
Evolutionary geneticist Svante Paabo speaks about the differences between chimp and humans and a genetic basis for language.
Geneticist Mary-Claire King talks about the similarities and differences between chimps and humans.
Geneticist Mary-Claire King talks about her discovery that chimps and humans are extremely similar at a molecular level.
Phylogenetic relationships of modern humans, Neandertals, and chimps.
There are only 50 human genes that have no homolog in chimps. Differences between the two species are, therefore, due more to changes in gene regulation.
Variation between mtDNA (HVR1) samples from chimp, Neandertal and human.
Comparison of genetic diversity in humans and chimpanzees, using sequences from 811 humans and 332 chimps.
Family tree image of human and chimp splitting off from a common ancestor.
Model organisms share with humans many key biochemical and physiological functions that have been conserved (maintained) by evolution.