Causes, Viruses: HPV, Galloway clip 2
Professor Galloway explains that viruses don't want to cause cancer, they just want to make more virus.
Denise Galloway, Ph.D., talks about HPV and its link to cervical cancer and how HPV infection affects normal cellular processes. â€œViruses don't want to cause cancer, they just want to make more virus. But this virus has really none of its own machinery for replication. And so the only way it can replicate itself is to be in a cell that's replicating, so that it can use the cellular replication machinery. So it gets into a cell and in order to make its viral proteins, it needs to push that cell into cellular replication. And it does so with the expense of the cell's normal control. Normally the outcome is that you get more virus. So cancer is actually a very rare outcome for HPV infection.â€
more virus, viral proteins, cervical cancer, cellular processes, galloway, replication, hpv
- ID: 1002
- Source: DNALC.IC
Professor Galloway explains that there are many HPVs that infect the genital tract and a set of those cause benign genital warts but another set is able to cause lesions that will go on and progress to cervical or other anal-genital cancers.
In this section learn how viruses contribute to cancer development.
David Baltimore and Howard Temin explain work on the Rous sarcoma virus.
David Baltimore, Howard Temin and Renato Dulbecco shared the 1975 Nobel Prize in Physiology or Medicine for the discoveries concerning the interaction between tumor viruses and the genetic material of the cell.
Mike Wigler shows how all organisms share similar genes, called homologs.
Howard Temin, David Baltimore and Renato Dulbecco shared the 1975 Nobel Prize in Physiology or Medicine for the discoveries concerning the interaction between tumor viruses and the genetic material of the cell.
Conventional cancer drugs are cellular poisons that block replication or some other aspect of cell growth. These drugs affect all cells – healthy or cancerous.
Explore the reverse transcriptase mechanism.
Professor Steinberg explains that HPVs are a family of related viruses, and they're small DNA tumor viruses that can cause tumors in either their natural host or another organism.
The 3-D animations in this Pathway to Cancer section focuses on a single pathway that regulates growth and protein production.