Biology & 3D Animation Library

DNA Transformation, continued

DNA transformation is a naturally occuring but rare event in which DNA can be transferred into bacteria. In 1970, Morton Mandel and Akiko Higa discovered a way to make E. coli more "competent" for transforming foreign DNA. Their calcium chloride method is widely used today to obtain high-efficiency transforming cells.

Stanley Cohen and Herbert Boyer inserted the recombinant DNA molecule they created into E. coli bacteria by means of a plasmid, thereby inducing the uptake and expression of a foreign DNA sequence known as "transformation."

e coli bacteria,dna transformation,dna molecule,herbert boyer,stanley cohen,recombinant dna,dna sequence,e coli,plasmid,expression

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  • ID: 15918
  • Source: DNALC
  • Download: swf

Related Content

16705. Animation 34: Genes can be moved between species.

Stanley Cohen and Herbert Boyer transform bacteria with a recombinant plasmid, and Doug Hanahan studies induced transformation.

  • ID: 15918
  • Type: animation
  • Source: DNALC.DNAFTB

16715. Video 34: Douglas Hanahan, clip 1

Improving on the Mandel and Higa method of DNA transformation.

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15916. DNA transformation

Stanley Cohen and Herbert Boyer inserted the recombinant DNA molecule they created into E. coli bacteria by means of a plasmid, thereby inducing the uptake and expression of a foreign DNA sequence known as "transformation."

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  • Type: animation
  • Source: DNALC.DNAFTB

16720. Biography 34: Stan Norman Cohen (1935 - )

Stan Cohen and Herb Boyer "invented" recombinant DNA technology.

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