This section reviews how epidemiologists look for cancer "hot spots" - regions with high cancer rates.
Despite the attention given to inherited cancer genes in the press, less than 10% of all cancers are inherited. Many other people would like to blame cancer on synthetic chemicals - but pollution, food additives, and industrial wastes account for less than 5% of cancers in the U.S. So what is really behind cancer? A world map can give surprising clues about cancer causes, as well as prevention. Although cancer affects people of all nationalities, epidemiologists look for cancer "hot spots" - regions with high cancer rates. Then they attempt to find environmental, dietary, cultural, or lifestyle factors that are common to the regions where cancers are most frequent. (Link to world map with prevalence of lung, liver, stomach, skin, breast, cervix, and colon/rectum cancers.)
spots regions, cancer genes, food additives, cancer rates, synthetic chemicals, lifestyle factors, world map, industrial wastes, nationalities, cancers, hot spots, pollution
- ID: 953
- Source: DNALC.IC
This section explains that lung cancer is the leading cause of cancer deaths in the United States and it is almost entirely preventable, since the vast majority of cases are due to cigarette smoking.
In order to identify cancer causes and prevention strategies, researchers conduct a cohort of studies where they collect information from large groups of individuals over many years.
Aflatoxin, a byproduct of molds, is a potent cancer-causing agent. Long-term exposure to aflatoxin has been linked to increased incidence of liver cancer.
In this section learn how diet can contribute and or be linked to the development of prostate cancer.
In addition to enzymes produced by the body, certain components in food can also react with damaging chemicals, and an increased consumption of these foods may lower a person’s risk of cancer development.
Matt Ridley talks about chromosome 13, BRCA2 gene for breast cancer susceptibility.
This section reviews K-ras and p53, two genes most frequently mutated in smoking-related lung cancers, one tar component, benzo[a]pyrene, is specifically linked to known mutations in these genes.
In this section learn how Aflatoxin a contaminating byproduct of mold caused liver cancer in animals and solicited strict guidelines to regulate the levels of Aflatoxin in the U.S. food supply today.
This section covers the smoking epidemic in the U.S. and the 163,000 Americans that die each year from lung cancer, which is greater than deaths caused by prostate, breast, colon, and pancrease cancers combined.
Professor Nelson discusses how ecological epidemiology evidence is utilized to determine cancer susceptibility.