Autism and Twin Studies (1)
Recent research into the causes of autism suggests that the disorder is predominantly genetically determined.
A 1995 study of autism in a British sample compared the rates of autism in monozygotic (identical) and dizygotic (fraternal) twins. The study found that for monozygotic (identical) twins, if one twin met the criteria for autism, then 60% of the time the other twin also met this criteria. For monozygotic twins, therefore, the concordance rate for autism was found to be 60%. By comparison, the concordance rate for dizygotic twins was 0%. Because monozygotic twins share all genes and dizygotic twins share on average 50% of their genetic information, this provides compelling evidence that autism is indeed predominantly genetically determined.
autism, genes, twins, monozygotic, dizygotic, identical, fraternal, concordance, Bailey, Couteur, Gottesman, Bolton, Yuzda, Rutter
- ID: 869
- Source: DNALC.G2C
Students learn about the symptoms associated with autism, explore the nature of 'normal' behavior, and can design a quasi-experiment to test a hypothesis about autism.
While many genes and loci have subsequently been found to associate with bipolar disorder, none have been unambiguously identified as causal.
An overview of autism-related content on Genes to Cognition Online.
Professor James Potash explains that twin studies dating back to the 1920s have identified bipolar disorder as a genetic disorder.
Professor Pat Levitt explains that twin studies of autism show that it is a highly genetic disorder.
Professor Eric Kandel explains that although identical twins have identical genes, different life experiences mean they do not have identical brains.
Professor Daniel Weinberger explains that while genes play an important role in susceptibility to schizophrenia, environmental interactions are also important.
Brain scans of close relatives of children with autism reveal clear abnormalities that parallel those seen in autism.
11743. "Eugenics and Society" (The Galton Lecture given to the Eugenics Society), by Julian S. Huxley, Eugenics Review (vol 28:1) (5)
"Eugenics and Society" (The Galton Lecture given to the Eugenics Society), by Julian S. Huxley, Eugenics Review (vol 28:1) (5)
Autism is a disorder in brain development that becomes apparent in earliest childhood. It is defined by problems in socialization, communication, and repetitive behaviors.