Fruit fly (Drosophila melanogaster)
The fruit fly is easy to maintain, has large numbers of offspring, and grows quickly. The fruit fly shares with humans a number of so-called â€œmaster,â€ or homeotic, genes.
The fruit fly is a small invertebrate. Although it cannot be frozen like bacteria and worms, it is easy to maintain, has large numbers of offspring, and grows quickly â€“ from embryo to adult in 12 days. The fruit fly shares with humans a number of so-called â€œmaster,â€ or homeotic, genes that control development of a complex, symmetrical body plan. Thomas Hunt Morgan and his students at Columbia University identified the first fruit fly mutations in the early 1900s. Since that time, scientists have developed a large library of genetic mutants. It is relatively straightforward to disrupt fruit fly genes and to introduce foreign ones. All of these features make Drosophila a powerful model organism for studying animal development and even elements of behavior â€“ including learning and memory!
fruit fly, drosophila melanogaster, model, systems, organisms, homeotic genes, thomas hunt morgan, mutations
- ID: 1719
- Source: DNALC.G2C
Model organisms share with humans many key biochemical and physiological functions that have been conserved (maintained) by evolution.
Thomas Hunt Morgan was one of the first true geneticists.
New York high school students set out to find Thomas Hunt Morgan's "Fly Room" at Columbia University, where seminal genetics research took place in the early 20th century.
Doctor Josh Dubnau explains that model systems are particular species of animals that substitute for humans or other animals. For genetic and historic reasons, the fruit fly is a commonly used model.
DNAFTB Animation 10:Thomas Hunt Morgan describes his discoveries using fruit flies.
Eric Wieschaus and Christiane Nüsslein-Volhard explain research of Drosophila's developmental stages, and Ed Lewis presents homeotic mutations.
Professor David Van Vactor discusses the properties that make the fruit fly (drosophila) a powerful model system.
Alfred Sturtevant was a student of Thomas Hunt Morgan. Sturtevant provided proof of genetic linkage.
Model organisms such as yeast, bacteria, the mouse and the fruit fly are used by researchers to study biological systems. The genomes of these organisms have been mapped and sequenced.
Calvin Bridges was a student of Thomas Hunt Morgan. Bridges advanced the theory of chromosomal non-disjunction, and did a lot of work on chromosomal banding patterns.