Polymerase chain reaction (PCR)

Polymerase chain reaction (PCR) enables researchers to produce millions of copies of a specific DNA sequence in approximately two hours. This automated process bypasses the need to use bacteria for amplifying DNA.

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  • ID: 17044
  • Source: DNALC

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15625. Polymerase chain reaction (PCR)

DNA polymerase (blue) makes many copies of DNA (red) in a cycle of the polymerase chain reaction (PCR).

  • ID: 17044
  • Type: animation
  • Source: DNAi

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The cycles of the polymerase chain reaction (PCR).

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  • Source: DNALC.DNAi

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The DNA sequencing method developed by Fred Sanger forms the basis of automated "cycle" sequencing reactions today.

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15138. Naming PCR

Kary Mullis explains how the polymerase chain reaction (PCR) was named.

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  • Type: animation
  • Source: DNAi

15624. Kary Mullis

Image of Kary Mullis. In 1985, Kary Mullis invented the polymerase chain reaction (PCR), a method of amplifying or producing many copies of a specific piece of DNA. The revelation came to this eccentric character on a drive in northern California.

  • ID: 17044
  • Type: animation
  • Source: DNAi

15140. Making many DNA copies, Kary Mullis

Kary Mullis talks about his discovery of the polymerase chain reaction (PCR), a process that allows chemists to produce many copies of a specific fragment of DNA.

  • ID: 17044
  • Type: animation
  • Source: DNAi

15666. Making GeneChipsĀ® at Affymetrix

The quartz wafer is in the holding position on the DNA synthesizer. The wafer is moved to a vertical reaction vessel for the process of DNA chain elongation.

  • ID: 17044
  • Type: animation
  • Source: DNALC.DNAi

16812. Animation 39: A genome is an entire set of genes.

James Watson describes sequencing the human genome using markers and BACs, and Craig Venter explains using cDNA libraries, ESTs, and shotgun sequencing.

  • ID: 17044
  • Type: animation
  • Source: DNALC.DNAFTB

16515. Animation 23: A gene is a discrete sequence of DNA nucleotides.

Fred Sanger outlines DNA sequencing.

  • ID: 17044
  • Type: animation
  • Source: DNALC.DNAFTB

15923. Cycle sequencing

The sequencing method developed by Fred Sanger forms the basis of automated "cycle" sequencing reactions today. Fluorescent dyes are added to the reactions, and a laser within an automated DNA sequencing machine is used to analyze the DNA fragments produc

  • ID: 17044
  • Type: animation
  • Source: DNAi