Interviewee: Kary Mullis. Kary Mullis explains how the polymerase chain reaction (PCR) was named. (DNAi Location: Manipulation > Techniques > Amplifying > Naming PCR)
The first record I have of it is when I made a computer file which I usually did whenever I had an idea, that would have been on the Monday when I got back, and I called it Chain Reaction.POL, meaning polymerase. That was the identifier for it and later I called the thing the Polymerase Chain Reaction, which a lot of people thought was a dumb name for it, but it stuck, and it became PCR.
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DNA polymerase (blue) makes many copies of DNA (red) in a cycle of the polymerase chain reaction (PCR).
Image of Kary Mullis. In 1985, Kary Mullis invented the polymerase chain reaction (PCR), a method of amplifying or producing many copies of a specific piece of DNA. The revelation came to this eccentric character on a drive in northern California.
Kary Mullis talks about his discovery of the polymerase chain reaction (PCR), a process that allows chemists to produce many copies of a specific fragment of DNA.
The cycles of the polymerase chain reaction (PCR).
Polymerase chain reaction (PCR) enables researchers to produce millions of copies of a specific DNA sequence in approximately two hours. This automated process bypasses the need to use bacteria for amplifying DNA.
KARY MULLIS (1944- )
Kary Mullis speaks about the process of find a specific fragment of DNA amongst many pieces in a complex mixture.
The DNA sequencing method developed by Fred Sanger forms the basis of automated "cycle" sequencing reactions today.
DNALC Live: Join us Monday, April 6th at 1:00 PM EDT for a virtual lab! Jeff will extract DNA from snack foods in an effort to detect GMOs through PCR. Watch and download worksheets to follow along here:
The quartz wafer is in the holding position on the DNA synthesizer. The wafer is moved to a vertical reaction vessel for the process of DNA chain elongation.