2D Animation of Antisense Oligonucleotide Therapy for SMA
An animation shows how antisense oligonucleotide therapy for SMA changes the way the SMN2 gene is spliced.
Spinal muscular atrophy, SMA, RNA, mRNA, splicing, gene, genetic, DNA, antisense, motor neuron, splice, Therapy, Alternative splicing, SMN2, exon, intron, transcript, restore, express, gene expression, promoter, suppressor, enhancer, silencer, oligonucleotide, antisense, inclusion, exon 7, axon
- ID: 16950
- Source: DNALC.SMA
Drs. Sharp and Sumner describe how RNA splicing can be used as a therapy for SMA.
Dr. Krainer explains the science behind antisense therapy for SMA.
An animation shows alternate splicing of the SMN2 gene.
Dr. Krainer explains the connection between SMA and RNA splicing.
Dr. Sumner explains how SMA is related to changes in the SMN1 and SMN2 genes.
A step-by-step 2D animation shows the details of RNA splicing.
Drs. Sharp and Krainer explain how genes can be alternatively spliced.
Dr. Sharp explains the process of RNA splicing.
Dr. Sumner describes small molecule therapies for SMA.
An animation of the crucial RNA editing step called splicing.