Video 38: Scott Lowe, clip 5
The importance of cell death in cancer.
Human homologue to C. elegans ced-4 gene.
How does p53, a tumor-suppressor gene, affect cell death?
The role of p53 in chemo- and radiotherapy given its role in programmed cell death.
Scott Lowe's research has shown how the regulation of the cell cycle affect cancer.
This series of animations shows how mutations in the p53 gene are found in 70% of lung tumors, the highest rate for any cancer.
Leland Hartwell describes how cells regulate the timing of growth and cell division. Bob Horvitz and Mike Hengartner explain control mechanisms for cell death.
How he ended up in Bob Horvitz's lab working on cell death.
This section explains that lung cancer is the leading cause of cancer deaths in the United States and it is almost entirely preventable, since the vast majority of cases are due to cigarette smoking.
All cancers are genetic, in that cancers are caused by genetic mutations in genes that lead to malignancy.