What is Tay-Sachs?
Mutations in the HEX A gene cause a disorder called Tay-Sachs, where a person's nerve cells deteriorate and finally die. The HEX A protein is necessary in the breakdown of large molecules called GM2 gangliosides, which are used to make nerve cell membranes. If the HEX A protein is missing or not functioning well, the GM2 gangliosides build up and become toxic to the nerve cell.
nerve cell membranes,tay sachs,nerve cells,chromosome 15,gangliosides,hex,mutations,molecules,protein
- ID: 15969
- Source: DNALC.DNAi
Related Content
15970. What causes Tay-Sachs?
Mutations in the HEX A gene cause a disorder called Tay-Sachs, where a person's nerve cells deteriorate and finally die.
15906. Tay-Sachs
Mutations in the HEX A gene cause a disorder called Tay-Sachs, where a person's nerve cells deteriorate and finally die.
15962. What causes neurofibromatosis 2?
The NF2 gene produces a protein, called merlin, in the schwann cells that wrap around the axons of nerve cells. Merlin is a tumor suppressor protein, involved in regulation of the cell's activities. If the merlin protein is mutated, the schwann cells can
15961. What is neurofibromatosis 2?
The NF2 gene produces a protein, called merlin, in the schwann cells that wrap around the axons of nerve cells.
15904. Neurofibromatosis 2
The NF2 gene produces a protein, called merlin, in the schwann cells that wrap around the axons of nerve cells.
15959. What is Neurofibromatosis 1?
NF1 is a large gene that encodes three slightly different neurofibromin proteins, found in nerve and muscle tissue
15960. What causes Neurofibromatosis 1?
NF1 is a large gene that encodes three slightly different neurofibromin proteins, found in nerve and muscle tissues.
1069. Receptor Molecules
Professor David Van Vactor describes the role of receptor molecules, which receive signals from outside the cell, passing the signal to the inside.
15708. petri dish, nerve, red blood cells
Petri dish, nerve, red blood cells.
15903. Neurofibromatosis 1
NF1 is a large gene that encodes three slightly different neurofibromin proteins, found in nerve and muscle tissues.