What causes beta-thalassemia?
The HBB gene encodes an important blood protein called beta globin. A person with beta-thalassemia carries a mutation in both copies of the HBB gene, completely halting production of the beta globin protein. Without beta globin, the important oxygen-carrying protein, hemoglobin, can not be made. Although oxygen can be carried by a less efficient form of hemoglobin, most of the affected red blood cells die.
protein hemoglobin,red blood cells,beta thalassemia,chromosome 11,blood protein,mutation,hbb,oxygen
- ID: 15937
- Source: DNALC.DNAi
Related Content
15936. What is beta-thalassemia?
The HBB gene encodes an important blood protein called beta globin. A person with beta-thalassemia carries a mutation in both copies of the HBB gene, completely halting production of the beta globin protein.
15907. Beta-thalassemia
The HBB gene encodes an important blood protein called beta globin.
15968. What causes sickle cell?
Mutations in the HBB gene on chromosome 11 can cause sickle cell.
15967. What is sickle cell?
Mutations in the HBB gene on chromosome 11 can cause sickle cell.
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Sickle cell anemia is a genetic disease that affects hemoglobin, the oxygen transport molecule in the blood.
16004. HBB/HBBS Structure Alignment
Alignment of the 3D structures of hemoglobin beta and sicklecell hemoglobin beta.
15498. Hemoglobin and sickle cell anemia, 3D animation with no audio
This animation shows hemoglobin proteins of a person with sickle cell anemia.
15708. petri dish, nerve, red blood cells
Petri dish, nerve, red blood cells.
15949. What is hemophilia?
The F8 gene produces a protein needed for blood clotting. People with hemophilia bleed longer when they are injured because they are unable to form stable blood clots. Mutations in this gene are responsible for more than 90% of hemophilia cases.
15950. What causes hemophilia?
The F8 gene produces a protein needed for blood clotting. People with hemophilia bleed longer when they are injured because they are unable to form stable blood clots. Mutations in this gene are responsible for more than 90% of hemophilia cases.