Beta-thalassemia

The HBB gene encodes an important blood protein called beta globin. A person with beta-thalassemia carries a mutation in both copies of the HBB gene, completely halting production of the beta globin protein. Without beta globin, the important oxygen-carrying protein, hemoglobin, can not be made. Although oxygen can be carried by a less efficient form of hemoglobin, most of the affected red blood cells die.

protein hemoglobin,red blood cells,beta thalassemia,blood protein,mutation,oxygen

  • ID: 15907
  • Source: DNALC.DNAi

Related Content

15936. What is beta-thalassemia?

The HBB gene encodes an important blood protein called beta globin. A person with beta-thalassemia carries a mutation in both copies of the HBB gene, completely halting production of the beta globin protein.

  • ID: 15936
  • Source: DNAi

15937. What causes beta-thalassemia?

The HBB gene encodes an important blood protein called beta globin. A person with beta-thalassemia carries a mutation in both copies of the HBB gene, completely halting production of the beta globin protein.

  • ID: 15937
  • Source: DNAi

15968. What causes sickle cell?

Mutations in the HBB gene on chromosome 11 can cause sickle cell.

  • ID: 15968
  • Source: DNAi

15967. What is sickle cell?

Mutations in the HBB gene on chromosome 11 can cause sickle cell.

  • ID: 15967
  • Source: DNAi

15532. Sickle cell anemia, 3D animation with narration

Sickle cell anemia is a genetic disease that affects hemoglobin, the oxygen transport molecule in the blood.

  • ID: 15532
  • Source: DNALC.DNAi

15498. Hemoglobin and sickle cell anemia, 3D animation with no audio

This animation shows hemoglobin proteins of a person with sickle cell anemia.

  • ID: 15498
  • Source: DNAi

16004. HBB/HBBS Structure Alignment

Alignment of the 3D structures of hemoglobin beta and sicklecell hemoglobin beta.

  • ID: 16004
  • Source: DNAi

15708. petri dish, nerve, red blood cells

Petri dish, nerve, red blood cells.

  • ID: 15708
  • Source: DNAi

15561. Katreece, sickle cell patient

Katreece (here at right) has sickle cell anemia. The causes of sickle cell have been known since the 1940s.

  • ID: 15561
  • Source: DNAi

15901. Hemophilia

The F8 gene produces a protein needed for blood clotting.

  • ID: 15901
  • Source: DNAi