The RNA experiment
Sydney Brenner, François Jacob and Matt Meselson's experiment showed that RNA was a copy of the information in DNA. As a messenger, RNA transported the information from the nucleus to the protein-making machinery in the cell.
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- ID: 15877
- Source: DNALC.DNAi
Matt Meselson also had a hand in Sydney Brenner's RNA experiment. He talks about the experiment and how they waited for James Watson's group to finished their RNA work before publishing.
RNA is an intermediary between DNA and protein.
François Jacob, Sydney Brenner and Matt Meselson worked on the role of mRNA. An on/off switch involving mRNA seemed a logical control point for protein production.
Sydney Brenner showed that mRNA was the unstable intermediate that carried the message from DNA to the ribosomes.
(Page 1 of 2) Sydney Brenner's letter to Matt Meselson where he lays out the experiment for mRNA isolation.
(page 2 of 2) Sydney Brenner's letter to Matt Meselson where he lays out the experiment for mRNA isolation.
Francis Crick describes RNA and its role and Paul Zamecnick explains protein synthesis.
In this first of a two-part clip, Sydney Brenner describes the information transfer problem from DNA to the protein-making machinery.
Sydney Brenner talks about James Watson's work on RNA.
Matthew Meselson and Franklin Stahl invented the technique of density gradient centrifugation and used this to prove that DNA is replicated semi-conservatively.