Walter Gilbert (1987)
Child prodigy and yet another physics convert, Gilbert was a Harvard physics professor who found himself spending more and more time in biology laboratories. His switch to biology helped foster a new generation of scientists.
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- ID: 15691
- Source: DNALC.DNAi
How Jacob and Monod showed the existence of the inhibitor (what Gilbert calls the repressor).
Jacob and Monod never identified the inhibitor, but Gilbert found it.
Phil Sharp and Richard Roberts shared the 1993 Nobel Prize for the discovery of the split gene theory.
Before Jacob and Monod, people thought the amount of protein in a cell was constant and proteins turned themselves off.
Jacob and Monod discovered that genes control the amount of protein in a cell.
Where did the idea of negative control come from?
What we know about gene regulation today.
To explain their data, Jacob and Monod had to hypothesize the existence of mRNA.
Bob Horvitz and Mike Hengartner used C. elegans to work out the mechanism of programmed cell death.
Doug Hanahan refined transformation methods for DNA uptake into bacteria.