Walter Gilbert (1987)

Child prodigy and yet another physics convert, Gilbert was a Harvard physics professor who found himself spending more and more time in biology laboratories. His switch to biology helped foster a new generation of scientists.

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  • ID: 15691
  • Source: DNALC.DNAi

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16697. Video 33: Walter Gilbert, clip 4

How Jacob and Monod showed the existence of the inhibitor (what Gilbert calls the repressor).

  • ID: 16697
  • Source: DNAFTB

16698. Video 33: Walter Gilbert, clip 5

Jacob and Monod never identified the inhibitor, but Gilbert found it.

  • ID: 16698
  • Source: DNAFTB

16549. Biography 24: Phillip Allen Sharp (1944- )

Phil Sharp and Richard Roberts shared the 1993 Nobel Prize for the discovery of the split gene theory.

  • ID: 16549
  • Source: DNAFTB

16694. Video 33: Walter Gilbert, clip 1

Before Jacob and Monod, people thought the amount of protein in a cell was constant and proteins turned themselves off.

  • ID: 16694
  • Source: DNAFTB

16696. Video 33: Walter Gilbert, clip 3

Where did the idea of negative control come from?

  • ID: 16696
  • Source: DNAFTB

16699. Video 33: Walter Gilbert, clip 6

What we know about gene regulation today.

  • ID: 16699
  • Source: DNAFTB

16700. Video 33: Walter Gilbert, clip 7

To explain their data, Jacob and Monod had to hypothesize the existence of mRNA.

  • ID: 16700
  • Source: DNAFTB

16695. Video 33: Walter Gilbert, clip 2

Jacob and Monod discovered that genes control the amount of protein in a cell.

  • ID: 16695
  • Source: DNAFTB

16807. Biography 38: Howard Robert Horvitz (1947 - )

Bob Horvitz and Mike Hengartner used C. elegans to work out the mechanism of programmed cell death.

  • ID: 16807
  • Source: DNAFTB

16722. Biography 34: Doug Hanahan (1951 - )

Doug Hanahan refined transformation methods for DNA uptake into bacteria.

  • ID: 16722
  • Source: DNAFTB