DNA nucleotides represented as wooden tiles
Changes in the DNA are reflected in the protein product. There is a correlation between what happens to the genetic sequence and the resulting protein sequence. So, there must be some sense to the way the DNA nucleotides are arranged. DNA is made up of four different nucleotides: adenine (A), cytosine (C), guanine (G), and thymine (T).
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- ID: 15681
- Source: DNALC.DNAi
A single nucleotide polymorphism, or SNP, occurs when two individuals in the population differ by a single letter in the DNA sequence.
Because it contains the directions for assembling the components of the cell, DNA is often thought of as the "instruction book" for assembling life.
Early sequencers used four different reactions to determine the placement of each of DNA's four bases - known as A, C, T & G - in the sequence.
Determine the sequence of DNA.
James Watson and Francis Crick explain how they solved the structure of DNA. Erwin Chargaff explain how he measured the levels of each of the four nitrogenous bases.
What happens in protein synthesis?
Seymour Benzer was able to map mutations within one phage gene and correlate the mutations with protein changes. This showed that the DNA sequence of a gene was aligned with protein sequence.
DNA nucleotides (black letter tiles) matched in groups of two to amino acids (red letter tiles).
Fred Sanger outlines DNA sequencing.
Blocks to bases, DNA Has Four Units.