COMT expression
Professor Daniel Weinberger explains that the schizophrenia candidate gene, COMT, is abundantly expressed in the hippocampus and prefrontal cortex.
Where is COMT expressed? So COMT is a gene that is turned on and off by the activity of a cell. And the cells that happen to have a lot of COMT in them are particularly the cells of the regions of the brain that are most implicated in schizophrenia - the prefrontal cortex and the hippocampal formation. And so nerve cells, neurons in these two parts of the brain, express, particularly abundantly, COMT.
COMT, gene, schizophrenia, expression, frontal, lobe, prefrontal, cortex, hippocampus, daniel, weinberger
- ID: 1169
- Source: DNALC.G2C
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