Dopamine and Schizophrenia
Professor Daniel Weinberger explains that dopamine is the major focus of biochemical research into schizophrenia.
There have been specific neurochemicals associated with schizophrenia. The one that is probably most often mentioned is a chemical called dopamine. Dopamine is a neurotransmitter in the brain that is one of these chemicals that sends signals between neurons. And dopamine has been shown to be the critical chemical that all currently available treatments, medical treatments for schizophrenia, target. All currently available medical treatments for schizophrenia reduce the activity of dopamine as a signal between neurons in the brain. And because all these drugs work through dopamine, at least to some degree, there has been a lot of interest in the possibility that dopamine is an important chemical in the basic cause of schizophrenia. We have yet to find that that is the case but this has been an area of a great deal of research.
dopamine, schizophrenia, biochemical, biochemistry, neurochemical, neurotransmitter, daniel, weinberger
Doctor Jon Lieberman discusses three neurotransmitters that have been associated with depression - dopamine, serotonin, and norepinephrine.
Professor Daniel Weinberger discusses the role played by the biochemical N-Acetylaspartate in schizophrenia.
Professor Philip Shaw discusses some of the main functions associated with the dopamine system, which include reward, punishment, and control of action and attention.
Professor Daniel Weinberger discusses evidence from a number of research areas that highlight the importance of the neurotransmitter glutamate in schizophrenia.
Professor Jeffrey Lieberman discusses the dopamine hypothesis, the predominant neurochemical theory of schizophrenia.
Professor Daniel Weinberger explains why the gene COMT, which detoxifies dopamine, is a candidate gene for schizophrenia.
An overview of schizophrenia-related content on Genes to Cognition Online.
Doctor Ellen Leibenluft discusses some of the biochemicals that have been associated with bipolar disorder, including dopamine, serotonin, and glutamate.
Doctor Daniel Pine makes the important point that the idea of a 'chemical imbalance' as a cause of disorders has pretty much rightfully been given up.
Professor Daniel Weinberger explains that schizophrenia has been called 'the cancer of mental illness' because of the severity of its impact.