Polymerase chain reaction (PCR) enables researchers to produce millions of copies of a specific DNA sequence in approximately two hours. This automated process bypasses the need to use bacteria for amplifying DNA.
This animation is featured in our "Spotlight Collection" on Polymerase Chain Reaction, along with video interviews with Kary Mullis, a 3D molecular animation of PCR, and several laboratory protocols.
This animation is also available as INTERACTIVE MEDIA .
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DNA polymerase (blue) makes many copies of DNA (red) in a cycle of the polymerase chain reaction (PCR).
The DNA sequencing method developed by Fred Sanger forms the basis of automated "cycle" sequencing reactions today.
The cycles of the polymerase chain reaction (PCR).
Kary Mullis explains how the polymerase chain reaction (PCR) was named.
Image of Kary Mullis. In 1985, Kary Mullis invented the polymerase chain reaction (PCR), a method of amplifying or producing many copies of a specific piece of DNA. The revelation came to this eccentric character on a drive in northern California.
Kary Mullis talks about his discovery of the polymerase chain reaction (PCR), a process that allows chemists to produce many copies of a specific fragment of DNA.
The quartz wafer is in the holding position on the DNA synthesizer. The wafer is moved to a vertical reaction vessel for the process of DNA chain elongation.
James Watson describes sequencing the human genome using markers and BACs, and Craig Venter explains using cDNA libraries, ESTs, and shotgun sequencing.
Fred Sanger outlines DNA sequencing.
Kary Mullis speaks about the process of find a specific fragment of DNA amongst many pieces in a complex mixture.