Cell division is essential for healthy growth of an organism and complex genetic mechanisms have evolved to switch cell division on and off at the proper time for normal development.
Duration: 50 seconds
Cell division is essential for healthy growth of an organism and complex genetic mechanisms have evolved to switch cell division on and off at the proper time for normal development. Cancer happens when cells divide uncontrollably and produce a growing lump or tumor. Tumors give out chemical signals that prompt the growth of blood vessels to supply them with oxygen and food. A particularly dangerous aspect of cancer is metastasis. Here, small pieces of the tumor break off and travel through the bloodstream to invade other parts of the body.
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Professor Robert Weinberg explains how cancer cells have to learn how to become angiogenic, that is to say attract blood vessels to grow into the tumor mass.
All cancers are genetic, in that cancers are caused by genetic mutations in genes that lead to malignancy.
Glutamate, one of the most abundant chemical messengers can inflict massive damage if it is accidentally spilled into brain tissue in large amounts.
Unlike any other organ, the brain depends on continuous blood flow. If the circulation to a portion of the brain is interrupted, that area will quickly lose its ability to function.
Sickle cell anemia is a genetic disease that affects hemoglobin, the oxygen transport molecule in the blood.
In Familial Adenomatous Polyposis, a complex cascade of events leads from an initial mutation in a “gatekeeper” gene, eventually to a malignant tumor.
Journey inside a cell as you follow proteins and learn about cellular interactions. This 3-D animation brings to life the inner workings of a fibroblast cell as it responds to external signals. Created by Cold Spring Harbor Laboratory and Interactive Know
Professor Douglas Hanahan discusses how cancer cells require a source of nutrients and oxygen, which is supplied through new blood vessel growth – the process of angiogenesis, which is critical for almost all cancers.
Cancer is a disease that affects people of all nationalities and age groups and all cancers start with mutations in one cell.
Developing a safe and effective therapy to protect the brain after a stroke, a process known as neuroprotection, represents a major unsolved challenge for researchers.