The amygdala - fear and stress response
Professor Bruce McEwen discusses how the amygdala is involved in processing fear and stress.
Starting with the amygdala, it is the brain area thatâ€™s involved in fear, fear learning, also to some extent in aggression. Itâ€™s also a brain structure that is involved in turning on the stress response, turning on the adrenaline, turning on the ACTH [adrenocorticotropic hormone] that causes cortisol secretion. Itâ€™s also an area thatâ€™s involved when youâ€™re stressed and see something dangerous, like a snake walking in the woods. You freeze and then you later move back. Itâ€™s involved in all of these primary actions that are related to stress and self-defense.
amygdala, aggression, self defense, adrenaline, secretion, acth, stress, response, bruce, mcewen
Professor Bruce McEwen describes some of the key players in the endocrine system - hypothalamus, pituitary gland, adrenal cortex, sex glands, and hormones.
Professor Bruce McEwen describes steps that can reduce stress, including sleep, exercise, and a healthy diet. The brain is the central organ of stress and differentiates positive, tolerable, and toxic stress.
Professor Bruce McEwen describes the endocrine system, which regulates hormones, the autonomic nervous and immune systems.
Professor Wayne Drevets outlines the amygdala's importance to the neurobiology of depression. He concludes that stimulation of the amygdala can elicit depression-like emotional experiences.
Professor Bruce McEwen describes the interplay between reilience and stress, which can cause the brain to shrink or grow.
Professor Bruce McEwen discusses differences between the sexes in coping with stress. These are mediated by hormonal, neural, and genetic factors.
Professor Bruce McEwen describes how the hippocampus and prefrontal cortex mediate the parasympathetic system, which is associated with risk-taking.
Professor Bruce McEwen outlines the environmental, genetic, and experiential factors that can cause tolerable stress to become toxic.
An overview of depression-related content on Genes to Cognition Online.
Professor Bruce McEwen notes that stimulation during early life can lead to a better cognitive outcome.