The simplicity of the cre/lox system.
How to cut out a gene and why would anyone want to.
How the idea of the cre/lox system come about.
Brian Sauer adapted the cre/lox recombinase system from phage for mammalian gene knock outs.
Man (Brian Sauer) and machine, 1982.
Bob Horvitz and Mike Hengartner used C. elegans to work out the mechanism of programmed cell death.
Mario Capecchi describes proteomics; the large-scale study of protein structure and function. Brian Sauer explains gene knock outs.
Bridging the gap between descriptions of human behaviors and underlying neural events has been a dream of both psychologists and neuroscientists for quite some time.
Brian Druker reflects on the importance of understanding the causes of cancer for developing new treatments.
Professor Pat Levitt describes how developmental and genetic research contribute to brain architecture.