Mike Wigler mugging for the camera.
Mike Wigler (R) with his older brother and pet dog.
Why look for a cancer gene in yeast?
Cancer genes are fundamental for cell survival.
Looking for the function of ras in frog eggs.
What is the function of ras?
What's a homolog?
What happens to the ras protein when the gene is mutated?
Mike Wigler and his group were among the first to clone and characterize human oncogenes.
Mike Wigler shows how all organisms share similar genes, called homologs.