Biography 37: Edward Lewis (1918-2004)
Ed Lewis was born in Wilkes-Barre, Pennsylvania. He became interested in biology while still in high school. He studied biostatistics at the University of Minnesota and received his B.A. in 1939.
After his doctorate degree from the California Institute of Technology in 1942, Lewis joined the United States Army Air Force. He served from 1942-45 as a meteorologist and oceanographer in the Pacific Theater, rising to the rank of Captain.
He returned to Caltech in 1946 as an instructor and has been a faculty member until his retirement in 1988. Most of his research on fruit flies was done at Caltech. Fruit flies were easy to work with and bred quickly. It was an ideal choice for studying genes involved in development. His work on homeotic genes earned him the 1995 Nobel Prize in Medicine or Physiology, which he shared with Eric Wieschaus and Christiane NÃ¼sslein-Volhard.
Lewis has also won other awards for his work including the 1987 Gairdner Foundation International Award, the 1990 National Medal of Science, and the 1991 Albert Lasker Basic Medical Research Award. He is a member of the National Academy of Sciences, the Genetics Society of America, the American Philosophical Society, and the American Academy of Arts and Sciences.
Lewis played the flute and was a member of the University of Minnesota's orchestra when he was an undergraduate.
Ed Lewis characterized one of the first homeotic mutations.
genetics society of america, gairdner foundation, nobel prize in medicine, homeotic mutations, american philosophical society, albert lasker, homeotic genes, fruit flies, volhard, ed lewis, eric wieschaus
- ID: 16781
- Source: DNALC.DNAFTB
Wieschaus' first meeting with Christiane NÃ¼sslein-Volhard and their early working relationship.
Wieschaus' comments on his friend and collaborator Christiane NÃ¼sslein-Volhard.
Eric Wieschaus and Christiane Nüsslein-Volhard explain research of Drosophila's developmental stages, and Ed Lewis presents homeotic mutations.
The "magic" number -- how many genes does a fly need for early embryonic development?
Wieschaus' first "personal" encounter with a fruit fly.
Eric Wieschaus and Christiane NÃ¼sslein-Volhard isolated and characterized many of the genes necessary for early embryonic development in Drosophila.
Christiane NÃ¼sslein-Volhard and Eric Wieschaus isolated and characterized many of the genes necessary for early embryonic development in Drosophila.
Generating the mutant fruit flies used in their experiments.
The results of the large-scale mutagenesis -- how many mutants and how many flies
The fruit fly is easy to maintain, has large numbers of offspring, and grows quickly. The fruit fly shares with humans a number of so-called “master,” or homeotic, genes.