Video 22: Marshall Nirenberg, clip 3
Marshall Nirenberg is a member of the National Heart, Lung, and Blood Institute of the National Institutes of Health.
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- ID: 16506
- Source: DNALC.DNAFTB
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Using charged tRNAs to prove triplet nature of the genetic code, and to determine the base sequences of codons
Doing the experiments to determine whether the genetic code is universal, and their subsequent philosophical impact.
Working out the 64 codon combinations: the joy of doing science at this time.
Finding out he won the Nobel prize.
Discovering that polyU directs the synthesis of polyPhenylalanine.
Explaining the experiment to determine the RNA able to direct the synthesis of proteins.
Marshall Nirenberg, National Institute of Health, 1960.
Marshall Nirenberg, Har Gobind Khorana, and Robert Holley shared the 1968 Nobel Prize for Physiology and Medicine. Nirenberg and Khorana cracked the genetic code. Holley sequenced and deduced the structure of the first tRNA molecule.
Igor Dawid, Acting Scientific Director of the National Institute of Child Health and Human Development.
Three DNA nucleotides form a codon and specifiy amino acids.