Chargaff's ratios, 3D animation with narration
Erwin Chargaff found that in DNA, the ratios of adenine (A) to thymine (T) and guanine (G) to cytosine (C) are equal. This parity is obvious in the final DNA structure. (DNAi Location: Code > Finding the Structure > Pieces of the puzzle > Chargaff's ratios > Chargaff's ratios)
The DNA molecule is made up of very long chains of the 4 bases: A, C, G and T. In 1950, Erwin Chargaff published a paper stating that in DNA of any given species, the ratio of adenine to thymine is equal, as is the ratio of cytosine to guanine. This is known as Chargaff's ratios and it was a crucial clue that helped solve the structure of DNA. Chargaff's ratios are universal: all forms of life obey this rule. Only the balance of A-T pairs and C-G pairs varies between species.
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- ID: 15495
- Source: DNALC.DNAi
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15492. Discovering the double helix structure of DNA, James Watson, video with 3D animation and narration
James Watson used cardboard cutouts representing the shapes of the DNA bases to figure out how bases pair.
15251. Discovering the rules of complementary base pairing, Erwin Chargaff
Erwin Chargaff talks about his discovery â a major step for building the DNA model.
15452. Discovering the double helix structure, James Watson
James Watson talks about how he worked out the base pairing of DNA.
16422. Animation 19: The DNA molecule is shaped like a twisted ladder.
James Watson and Francis Crick explain how they solved the structure of DNA. Erwin Chargaff explain how he measured the levels of each of the four nitrogenous bases.
16421. Concept 19: The DNA molecule is shaped like a twisted ladder.
Deoxyribose and phosphate molecules form the uprights and nucleotide pair form the rungs of the DNA ladder.
Because it contains the directions for assembling the components of the cell, DNA is often thought of as the "instruction book" for assembling life.
15250. Complementary base pairing, Erwin Chargaff
Erwin Chargaff talks about his name for Chargaff's ratios.
15533. DNA Has Four Units, 3D animation
Blocks to bases, DNA Has Four Units.
16012. Erwin Chargaff, 1950
The DNA molecule is shaped like a twisted ladder.
16429. Gallery 19: Erwin Chargaff, 1947
Erwin Chargaff was the first to accurately measure nucleotide amounts in DNA.