DNA donors for sequencing at Celera, Craig Venter
Interviewee: Craig Venter. Craig Venter, the leader of the private genome effort at Celera Genomics, talks about the sources of the DNA used in their sequence. (DNAi Location: Genome > The project > Players > Private project > The private project's DNA donors)
We chose three females and two males, and we had people of self-described ethnic backgrounds as African, American, Hispanic, Chinese and Caucasian. Obviously I was one of the Caucasians. The 27 million sequences that we generated at Celera were a combination from libraries made from these five different individuals. One sequence more than the others comprised the basic sequence, because we were worried about the polymorphic variation, the changes in, you know, one genetic code versus the other that could complicate our assembly. And so we wanted to make sure that instead of having equal numbers from all the people, that we had one sequence that was more derived from one individual, so we'd be assured that the mathematics would work.
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Craig Venter, the leader of the private genome effort, talks about the "whole genome shotgun" technique that was used by Celera Genomics to sequence the human genome.
Craig Venter, leader of the private effort at Celera Genomics, speaks about his company's reliance on the public data for reassembly of the Celera sequence.
The leaders of the private and public genome projects, Craig Venter and Francis Collins.
Craig Venter speaks about the public sector's reaction to his plans to sequence the genome at a private company, Celera Genomics.
Craig Venter, the leader of the private genome effort at Celera Genomics, talks about the differences between the public and private approaches.
Craig Venter, leader of the private effort at Celera Genomics, speaks about the excitement the race to sequence the human genome generated.
Craig Venter talks about working with repeats.
Origins of the EST project.
Eric Lander, director of the Whitehead Institute Center for Genome Research, explains where the DNA donors for the first reference sequence came from.
Commentators on the genome sequence (Human Genome Project). Top: William Clinton, Ewan Birney, John Sulston. Bottom: Jim Watson, Craig Venter.