Classical and Operant Conditioning

Doctor Josh Dubnau describes the difference between operant and classical conditioning, which are two different learning paradigms often studied in scientific laboratories.

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1428. Genes for Memory

Doctor Josh Dubnau explains that genes are responsible for memory in that they contain the raw instructions for memory. Experience determines how these instructions are assembled.

  • ID: 1428
  • Source: G2C

1427. Learning - What is Learning?

Doctor Josh Dubnau describes learning as a change in an animal’s behavior in response to previous stimuli or experience.

  • ID: 1427
  • Source: G2C

1432. Stages of Memory

Doctor Josh Dubnau explains that memories seem to be formed in different stages that evolve over time. These include acquisition, short-term storage, and consolidation.

  • ID: 1432
  • Source: DNALC.G2C

1437. The Shibire Experiment

Doctor Josh Dubnau describes how he and his colleagues at Cold Spring Harbor Laboratory devised an experiment that dissociated the encoding and retrieval of memory in fruit flies.

  • ID: 1437
  • Source: G2C

1435. Mutant Screens

Doctor Josh Dubnau explains that mutant screens generate a large panel of mutant animals that average a mutation in one gene. Each animal is then tested for a particular characteristic.

  • ID: 1435
  • Source: G2C

1434. Do Flies Have Cognition?

Doctor Josh Dubnau discusses some remarkably sophisticated behaviors in fruit flies that suggest that they do have cognition.

  • ID: 1434
  • Source: G2C

1426. Memory - Creating Memories

Doctor Josh Dubnau explains that memories result from rapid changes in the connections in a huge network of neurons. We do not know, however, the precise mechanism driving these changes.

  • ID: 1426
  • Source: G2C

1439. Biochemicals - Excitation and Inhibition

Doctor Josh Dubnau explains that the genes active in different neurons can make them excitatory (e.g. glutamate) or inhibitory (e.g. GABA). These neurotransmitters are critical to learning.

  • ID: 1439
  • Source: G2C

1436. Disentangling Encoding and Retrieval

Doctor Josh Dubnau explains that memories may be present (encoded) but not accessible (retrievable). Scientists have devised a number of experiments for teasing apart encoding from retrieval.

  • ID: 1436
  • Source: G2C

1433. What are Model Systems? (1)

Doctor Josh Dubnau explains that model systems are particular species of animals that substitute for humans or other animals. For genetic and historic reasons, the fruit fly is a commonly used model.

  • ID: 1433
  • Source: G2C