Neuroimaging - notes of caution
Doctor Thomas Insel points out that although neuroimaging is a tremendously exciting technique, there are no examples of findings affecting clinical practice or diagnosis.
There is a huge amount of excitement around neuroimaging. It has in a way taken us into an era where the brain is no longer a black box. What an exciting time it is to be able to say, 'How is the human brain working at a systems level?', and seeing the networks and seeing how people with depression or schizophrenia or dementia are different than those without. Even now, with these longitudinal studies, seeing changes in the brain over time and how they emerge for people who are at risk for Alzheimerâ€™s disease or people who develop schizophrenia, weâ€™re just beginning to see this. So a huge amount of potential here. I am excited about it but I think there has to be some caution. Weâ€™ve had 19 thousand imaging papers since 1991. Currently about 4 papers a day on average are being published in neuroimaging, and I canâ€™t point to a single paper thatâ€™s affected practice; thatâ€™s changed the way we diagnose or treat depression, schizophrenia, autism, bipolar disorder, or any anxiety disorder. Thatâ€™s a problem because I would give you a very different story for cancer, heart disease and some neurological illnesses where actually neuroimaging has turned out to be extremely important. But at this point in 2008, itâ€™s more promise than actual deliverance. We donâ€™t yet have the ability to use neuroimaging in the way we need to, which is to affect practice either because it gives us earlier diagnosis or it helps us to select a treatment.
neuroimaging, imaging, brain scan, diagnosis, thomas insel
- ID: 2004
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2005. Alzheimer's - closing in on early diagnosis
Doctor Thomas Insel discusses recent findings of structural changes in the brains of teenagers may be warning signs for the potential onset of Alzheimer's disease.
2187. Alzheimer's disease - imaging test
Professor Donna Wilcock discusses a new biological technique for diagnosing Alzheimer's disease using PET neuroimaging.
1184. Imaging the Schizophrenic Brain
Professor Jeffrey Lieberman discusses how neuorimaging studies are providing fresh insights into brain structures associated with schizophrenia.
800. Imaging Alzheimer's Disease
Neuroimaging techniques help scientists visualize Alzheimer's disease before the disease becomes debilitating.
1153. Functional Magnetic Resonance Imaging (fMRI)
Professor Trevor Robbins describes functional magnetic resonance imaging (fMRI) technology, which is used to take detailed images of the functioning brain.
864. Imaging Technology
Images from brain scans and new microscopy techniques are offering a strikingly clear glimpse of what’s going on underneath the bumpy surface of our skulls.
1152. Positron Emission Tomography (PET)
Professor Trevor Robbins discusses how positron emission tomography (PET) works to provide detailed images of brain structure and chemistry.
2276. Functional Magnetic Resonance Imaging (fMRI)
Doctor Johan Jansma demonstrates functional magnetic resonance imaging (fMRI), a key neuroimaging technique.
2011. Vasopressin, oxytocin and bonding (2)
Doctor Thomas Insel continues his discussion of the two neuropeptides, vasopressin and oxytocin.
2090. CT scans
Professor Wayne Drevets explains that computed tomography (CT) can still be used clinically. As a research tool however, it does not have the requisite tissue or spatial resolution.