Using tandem repeats for DNA fingerprinting, Alec Jeffreys
Interviewee: Alec Jeffreys. Alec Jeffreys (the "inventor" of DNA fingerprinting) explains repeats. (DNAi Location: Applications > Human identification > Profiling > DNA variations and fingerprints >Tandem repeats)
I guess we're now at about 1980, 1981, it was pretty obvious to me that, in principle, that the solution is going to lie in tandem repeat DNA, this is where you've got a short block of DNA sequence repeated over and over again. And that would then open up the possibility that that DNA could vary, not in the sequence but in the number of these stutters or repeats. And that would give you the possibility of not just two different versions like an A and a T, but tens, hundreds, maybe even thousands of different versions. So you could have one version with 10 stutters and one with 15 and one with 126 and one with 492.
alec jeffreys,dna sequence,location applications,dnai,stutters,interviewee,fingerprints,variations,tens,principle
Alec Jeffreys talks about how he came up with the name.
Alec Jeffreys talks about other scientists' reactions to his method.
Alec Jeffreys talks about the difficulties of the case.
Alec Jeffreys talks about making his first DNA fingerprint.
Alec Jeffreys talks about DNA fingerprinting after the Ghana case.
Alec Jeffreys talks about the resolution of the Ghana case.
DNA profiling, DNA fingerprinting, gel analysis
How a DNA fingerprint like this was made.
An image of Alec Jeffreys.
DNA profiling, DNA fingerprinting.