Drug Treatments for Schizophrenia
Professor David Lewis explains the difference between first and second generation drug treatments for schizophrenia.
So, of the anti-psychotic medications that we have available, the initial drug was Thorazin, which was actually discovered by accident in the early 1950s. These drugs are also called neuroleptics because they produce a number of motor side effects, including stiffness and rigidity and a tremor â€“ symptoms that are similar to Parkinsonâ€™s disease. In an attempt to develop drugs with similar efficacy or similar effectiveness against the psychotic symptoms of the illness, second generation anti-psychotics were developed. These lack, generally, the motor side effects, so they donâ€™t produce the stiffness and the tremor in individuals with schizophrenia. Unfortunately, weâ€™re now discovering that they do have a side effect profile of their own, which produces some limitations in their use.
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