[YouTube login required to chat]

Activity description:

Phenylthiocarbamide (PTC) is a bitter substance that only certain people can taste. This three-part series will explore the genetics behind a single nucleotide polymorphism (SNP) of the taste receptor, TAS2R38, that affects an individual’s ability to taste PTC. Guided by DNALC instructor Catherine Zhang, you will use the PTC case study to better understand classical Mendelian inheritance, and the use of SNPs in pharmacogenetics to help predict drug responses.

In this DNALC Live session, you will:

• Explore the relationship between genotype and phenotype

• Discover how single-nucleotide polymorphisms can be used to predict drug responses (pharmacogenetics)

• Learn how to predict bitter tasting ability through genotyping

• Observe how to score the bitter tasting ability phenotype with PTC paper

• Learn several experimental and bioinformatics methods in modern biological research

Downloads:

Links: