Regeneron DNA Learning Center

Fall Open Houses at the Regeneron DNALC!

Join us at an Open House to tour the new Regeneron DNALC, meet some educators and learn about our programs! RSVP is required. Choose a date and click below to register on Eventbrite:
Wed, Nov 10, 2021
3:00 PM–5:00 PM EDT
 Thu, Nov 18, 2021
3:00 PM–5:00 PM EDT

Visitors must provide proof that they are fully vaccinated.

About Regeneron DNALC

In-person

Bacterial Transformation and DNA Restriction Analysis
Teacher Professional Development in Genetics and Biotechnology

Election Day: November 2, 2021, 8:30 a.m.–2:30 p.m. EDT
Regeneron DNA Learning Center, Sleepy Hollow, NY

Bacterial Transformation

This experiment illustrates the direct link between an organism's genetic complement (genotype) and its observable characteristics (phenotype), and demonstrates how genetic engineering is used to produce human proteins such as insulin. In this lab you will introduce genes for antibiotic resistance and fluorescence into the bacterium E. coli. Following overnight incubation, transformed bacteria can be compared to control bacteria for their ability to grow in the presence of ampicillin and glow when exposed to UV light.

DNA Restriction Analysis

This experiment demonstrates that DNA can be precisely manipulated and that it behaves as predicted by the Watson-Crick structure. You will use restriction enzymes, the scissors of molecular biologists, to cut bacteriophage lambda DNA. The resulting DNA fragments will then be analyzed by agarose gel electrophoresis. Through comparison of DNA digest patterns and restriction maps, you will be able to identify a “mystery” enzyme.

These experiments directly correlate with lab requirements for Living Environment and AP Biology courses and align with the New York State Science Learning Standards, with an emphasis on analyzing and interpreting data, planning and carrying out investigations and the structure and function relationship. Guided by an experienced DNALC educator, training will focus on lab skills, conceptual connections, and classroom implementation.

*Participants will receive a Certificate of Completion and CTLE hours.
*Participants must provide proof that they are fully vaccinated. You will receive a link by email to upload this documentation directly to the DNALC. Masks are required at the DNALC.

  • Free workshop
  • Election Day: November 2, 2021
  • 8:30 a.m.–2:30 p.m. EDT
  • Regeneron DNA Learning Center
    1 Rockwood Road, Sleepy Hollow, NY
  • Directions

Register on Eventbrite

In-person

Human Mitochondrial Sequencing
Teacher Professional Development in Genetics and Biotechnology

Election Day: November 2, 2021, 8:30 a.m.–2:30 p.m. EDT
Regeneron DNA Learning Center, Sleepy Hollow, NY

Human Mitochondrial Sequencing

Comparison of the control region within the human mitochondrial genome reveals that people have distinct patterns of single nucleotide polymorphisms (SNPs). These sequence differences, in turn, are the basis for far-ranging investigations on human DNA diversity and the evolution of hominids. In this workshop you will prepare a sample of your own DNA from cells obtained by saline mouthwash, use PCR to amplify a section of your own mitochondrial DNA and confirm the result with agarose gel electrophoresis. Your DNA will then be sent for sequencing, and results uploaded to the DNALC’s BioServers website. You will learn how to perform bioinformatic analysis of your DNA sequence to explore the theories about how modern humans evolved and how related you are to your “classmates” and people from around the world.

This experiment directly correlates with lab requirements for AP Biology and aligns with the New York State Science Learning Standards, with an emphasis on analyzing and interpreting data, planning and carrying out investigations and the structure and function relationship. Guided by an experienced DNALC educator, training will focus on lab skills, conceptual connections, and classroom implementation.

*Participants will receive a Certificate of Completion and CTLE hours.
*Participants must provide proof that they are fully vaccinated. You will receive a link by email to upload this documentation directly to the DNALC. Masks are required at the DNALC.

  • Free workshop
  • Election Day: November 2, 2021
  • 8:30 a.m.–2:30 p.m. EDT
  • Regeneron DNA Learning Center
    1 Rockwood Road, Sleepy Hollow, NY
  • Directions

Register on Eventbrite