Francois Jacob and drawing
Francois Jacob draws out the control mechanism he co-discovered. In the 1960s, the control of protein production was figured out for a sugar metabolic pathway in bacteria. Bacteria turn on the production of an enzyme called beta-galactosidase when the sugar galactose is a food source. The mechanics of this type of genetic control are applicable to single-celled organisms like bacteria. However, the general principles of how genetic control works also apply to higher-order cells.
single celled organisms,beta galactosidase,francois jacob,jacob francois,metabolic pathway,protein production,genetic control,galactose,control mechanism,food source,general principles,bacteria,1960s,mechanics,cells,drawing
- ID: 15687
- Source: DNALC.DNAi
Francois Jacob and Jacques Monod figured out how bacteria controlled the production of an enzyme called beta-galactosidase. This system of feedback and negative regulation became the lac operon and was the first model for the control of protein productio
The first model for the control of protein production was the lac operon. This system of feedback and negative regulation is used by bacteria, however, the general principles also apply to higher organisms. Another method of protein regulation involves
Small image of Francois Jacob's lac operon drawing.
Jacques Monod and Francois Jacob work with how bacteria breaks large sugars into smaller pieces.
François Jacob talks about designing bacteria.
Francois Jacob and Jacques Monod were the first to discover how genes were turned on and off.
François Jacob talks about bacterial mutants that could not metabolize lactose. Using these mutants, Jacob and Monod figured out how protein production is controlled.
Sydney Brenner, Francois Jacob and Matt Meselson's experiment showed that RNA was a copy of the information in DNA. As a messenger, RNA transported the information from the nucleus to the protein-making machinery in the cell.
Genes can be turned on and off.
Francois Jacob, Cold Spring Harbor, 1953 meeting. Source: Cold Spring Harbor Laboratory Archives.