February Winter Break Fun

at the Dolan DNA Learning Center in Cold Spring Harbor!

We are excited to welcome students to the DNALC for these in-person programs! To learn more about the DNA Learning Center’s on-site COVID safety procedures, open On-site Procedures for Parents.

Eventbrite is used for February Winter Break registration and payment.

  • Reservations for each session must be made through Eventbrite.
  • Sessions are $25 per session, plus Eventbrite registration fee.
  • Sessions for 5–8 grades are scheduled in the mornings, and 9–12 grades in the afternoons.
  • Seats for each session are limited to 8 students and are filled on a first-come, first-served basis.
  • Parents will receive an email prior to registered programs with instructions for drop off and daily health surveys.

Thursday, February 18, 2021
Today's classes are not being held due to weather closure

RESCHEDULED DNA Fingerprinting

Grades 5–8

Human DNA is more alike than different, so how do we find the differences? Restriction enzymes are proteins that recognize specific DNA sequences and can be used to determine whether a particular DNA sequence is present. In this lab, DNA from “evidence” and “suspects” will be compared using restriction enzyme digest and agarose gel electrophoresis. DNA analysis will then be combined with crime scene data to draw conclusions about each suspect.

Details:

  • RESCHEDULED Thursday, February 18, 2021, 9:30–11:30 am EST
    NEW DATE: Thursday, February 25, 2021, 3:30–5:30 pm EST REGISTER for 3:30-5:30
  • Appropriate for grades 5–8
  • $25 per student

CANCELLED Detecting Genetically Modified Foods

Grades 9–12

Genes that encode herbicide resistance, insect resistance, drought tolerance, frost tolerance, and other traits have been added to many commercial plants—including most of the corn and soybeans grown in the United States. In this lab, you will isolate DNA from common foods and use polymerase chain reaction (PCR) to identify the presence or absence of transgenes. Results for this lab will be posted to the DNALC Field Lab website after class for analysis at home.

Details:

  • CANCELLED Thursday, February 18, 2021, 2:30–4:30 pm EST
  • Appropriate for grades 9–12
  • $25 per student

Friday, February 19, 2021

Gene Therapy

Grades 5–8

E. coli bacteria can usually digest the dairy sugar lactose, but we have mutant bacteria that are lactose intolerant! In this experiment you will genetically engineer the bacteria with a gene to produce the lactase enzyme they are missing, and they will become lactose "tolerant"! This is similar to an experimental method of replacing or supplementing genes to cure genetic disease, called gene therapy. By giving the bacteria new genes, you will be "curing" their genetic disorder.

Details:

  • Friday, February 19, 2021, 9:30–11:30 am EST
    REGISTER for 9:30-11:30
  • Appropriate for grades 5–8
  • $25 per student

Restriction Analysis

Grades 9–12

The DNA restriction analysis experiment demonstrates that DNA can be precisely manipulated and that it behaves as predicted by the Watson-Crick structure. In this lab, restriction enzymes—the scissors of molecular biology—are used to digest DNA from the bacteriophage lambda. Agarose gel electrophoresis will allow for visualization of the results.

This lab is required by the College Board as part of the Genetics and Information Transfer unit in AP Biology, and the technique is also introduced in the Biotechnology unit of the NYS Regents Living Environment course.

Details:

  • Friday, February 19, 2021, 2:30–4:30 pm EST
    REGISTER for 2:30-4:30
  • Appropriate for grades 9–12
  • $25 per student